What South American countries have you visited? (English to Spanish)
 

"What South American countries have you visited?"

"Qué países de Sudamérica usted ha visitado?"

It's OK because Spanish its pretty elastic about word order and you are free to choose among several options, but "¿Qué paises de Sudamérica ha usted visitado?" or " ... ha visitado Usted?" are better.

That freedom makes using opening "¿" and "¡" marks a non-optional thing.

Also, to me:

South American = Sudamericano

Of South America = De Sudamérica.

Thank you!