As far as I can think of, the use of the verb + de lleno usually has the sense of hitting a mark, spot, etc. but with a strong force behind it.
e.g El vendaval sopló de lleno en la ciudad de Valencia.
The gale hit Valencia with full force. (can't think of a better translation ATM)
La bomba cayó de lleno sobre el edificio del parlamento.
The bomb fell right on the parliament building.
As Irmamar said: La crisis ha dado de lleno en la construcción (in Spain at least).
The crisis has hit the construction industry hard.
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"Desiderata" - ...be gentle with yourself.You are a child of this universe no less than the trees and the stars; you have a right to be here.
...sé amable contigo mismo. Eres una criatura de este universo al igual que los árboles y las estrellas; tienes derecho a estar aquí.
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